Lifestyle drugs have been a much debated segment of therapeutics for the pharmaceutical industry primarily due to the issues surrounding their inclusion in drug payment plans and diversion of resources for their research. These drugs have been a point of contention also because of a lack of clarity in defining them. For the purpose of this report, lifestyle diseases have been defined to include a range of indications that affect an individuals quality of life even though they may not be deemed a medical problem.
The market was led by the MDD therapeutic segment followed by hormonal contraceptives. The smallest indication among the lifestyle disorders was alcohol dependence. The overall market was $37.2bn but is forecast to decline, albeit with a low single digit CAGR over the 2008-14 period.
Lifestyle disorders are marked by slowed R&D process and limited investigational products though MDD reflects some differences to this scenario. Each of the therapeutic indication s considered in this report reflects a markedly different scenario that substantiates the investment case around them. For instance:
In the antidepressants market , the older antidepressants such as tricyclic s and monoamine oxidase inhibitors, have given way to agents that target metabolism, storage and release neurotransmitters such as serotonin and norepinephrine.
In case of obesity, compounds with novel mechanisms of action such as GLP-1 pathway, monoamine transmission, PTP-1B receptor and melanin system, are being investigated.
The hormonal contraceptives market is marked with little R&D that has led to gaps in contraceptive technology. The industry needs to invest in contraceptives with better side-effects profile to aid compliance.
Growth of the erectile dysfunction market would be determined by the market dynamics ensuing between Viagra, Cialis and Levitra.
In the smoking cessation market, growth prospects of the leading brands such as Pfizers Chantix, are likely to be determined by the markets response to the black box label warnings on neuropsychiatric effects, introduced in July 2009.
Key features of this report
Epidemiological analysis of the therapeutic segments and forecast prevalence over the period 2008-14
Forecasts and analysis of the key products in the lifestyle disorders market over the period 2008-14, across major classes of treatments
Overview of key events in the global lifestyle disorders market that have impacted treatment trends and sales potential.
Strategic and growth analysis of leading pharmaceutical corporations based on sales focus by drug class, currently marketed products and R&D product portfolios
Detailed analysis of the major classes of treatments across all the therapeutic segments analyzed in the report
Detailed analysis of the clinically differentiated products in the lifestyle disorders market pipeline and sales forecast of key R&D pipeline products in the global lifestyle disorders market
Microsoft Dynamics GP, formerly known as Great Plains Dynamics and eEnterprise US Payroll module requires periodic payroll tax rates update. For large number of employees in your organization, especially when you have locations in multiple US states, you probably want to do quarterly tax update. If you are current with Microsoft Business Solutions annual support plan, you have access to Payroll Tax update utilities through your GP Customer Source. If you are no longer enrolled in annual support plan, you should check with your current Dynamics GP VAR if your current Great Plains version is still supported and you could receive Tax Updates from your GP Reseller. In this small publication we would like to give you the idea on limited payroll tax update service for old versions of Great Plains Dynamics GP:
1.Payroll Tax Rate Tables in Dynamics database. Tax rates are stored in system database of Great Plains, which is Dynamics. So, updates is done only once on the system level, and it should take effect immediately for all your companies
2.Limitations of Tax Update for old versions. GP versions 8.0, 7.5, 7.0, 6.0, 5.5, 5.0, 4.0 and earlier are no longer supported by Microsoft and Payroll Tax update download is not available for these versions. However, you should expect that some of the States changed their Tax calculation formulae and it is not possible to use old formulas, incorporated in Dynamics.DIC business rules logic. At this time we are aware about Missouri, so if your employees are there, please consider reenrolling to MBS support plan and upgrade your Dynamics GP to supported version 10.0 or 9.0. The other option would be to request GP Dexterity custom programming to update Tax Calculation formula in your old Great Plains version
3.Tax Rates Update Technology. We do understand your situation and we copy current tax rates to custom table and then from there we update your outdated tax tables in Dynamics database. This procedure typically requires four hours of Great Plains Technical Consultant time
4.Tax Update for Pervasive SQL and Ctree databases. This update requires some help from your IT department. Our preferred method is to use Microsoft SQL Server 2000 Enterprise Manager, create Linked Server to your Pervasive SQL or Ctree database, and update tax tables through heterogeneous SQL Update statement. If this is your case, please budget eight hours for the procedure. A bit more exotic case is when you host your Great Plains in Mac Faircom Server (Ctree)
Ford Cars one of the best International passenger car maker yet to make a marked presence in Indian Automobile Sector
With a market share of 3.5% in Indian passenger car market, Ford India has 4 models Figo, Fiesta Classic, New Fiesta and Ford Endeavour in its portfolio
With the entry level hatchback Figo in both Petrol and Diesel models Ford India though has been able to increase the sales but yet to achieve a substantial share in Indian passenger car market. However, the class and technology of Ford cars are world class one of the main reasons of low growth is a high concentration on entry segment hatchbacks in India. With a huge network Maruti Suzuki and Hyundai along with Tata Motors captures over 2/3rd of the market share, rest car market is spread among various car manufacturers looking for a pie Honda Siel Cars, Chevrolet India, Fiat, Nissan, Renault, Toyota, Skoda, Volkswagen, Mahindra & Mahindra and luxury segment of Audi, BMW and Mercedes Benz
Ford India as per its future strategy seems to have an all aggressive plans with upcoming launch of Ford Eco sport along with Ford Endeavour in Indian car market. The proposed classification strategy of Ford cars seems to be
a) Entry Segment will have Ford Figo
b) Mid Entry Sedan Segment will have Fiesta Classic
c) Mid Sedan will have New Fiesta
d) Entry Level SUV will have Upcoming Launch of Ford Eco Sport
e) High End SUV in budget of Rs. 20 Lac will see Ford New Endeavour coming in Indian Car market
Chevrolet India, the very next competition to Ford also has market share under 4% , but with higher number of models Spark, Beat, Uva, Aveo, Tavera, Optra, Cruze and Captiva. Chevrolet India another American car maker is yet to make a marked presence in Indian car market. However, the new Captiva and Trail blazer will change the dynamics of Indian automobile Industry in SUV Segment which is been captured by Toyota Fortuner.
The dynamics of Indian Automobile Industry is poised to change with almost 50 new models or facelift models are expected in next 12 months. With the market share tilted towards Maruti Suzuki commanding over 40% of passenger car market in India. With new models coming in it will by sure make the presence of American and European car makers Volkswagen and Skoda to see an enhance market share as part of business strategy.